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· Assessment of 17 primary and secondary risk factors
· Ratios of atherogenic to anti-atherogenic lipids, lipoproteins and apolipoproteins
· Requires only a single overnight fasting blood draw
· Includes patient-friendly results and commentary
· Results are presented in a clear, easy-to-understand report which details target ranges and graphically illustrates areas of elevated risk.
Prevalence of Cardiovascular Disease
Each year, cardiovascular disease (CVD) is associated with more deaths than all cancers—and more deaths in women than breast cancer. Unfortunately, diagnosis is typically made in the advanced stages of the disease, after it has progressed for decades. Even though Heart Disease appears to involve a strong familial component, early detection and reduction of risk factors are exceedingly important.
This Comprehensive Cardiovascular Risk Profile provides extensive evaluation of biomarkers of abnormal lipoprotein metabolism, inflammation, coagulation, glomerular filtration and glucose homeostasis, as well as the status of magnesium, iron and key antioxidants.
Risk Factors and Analysis
Total and LDL cholesterol, total triglycerides and HDL cholesterol have traditionally been measured to gauge CVD risk with plaque buildup. However, recent research indicates that more focused biomarkers can provide even greater insight. For example, oxidized LDL and small dense LDL have been found to be higher in CVD patients and correlated with the severity of CVD. In addition, levels of apolipoproteins A1 and B, specific protein constituents of HDL and LDL, are also strong indicators of risk.
Arterial damage is associated with the infiltration of white cells into vessel walls and inflammation, which increases blood levels of two acute phase proteins, C-reactive protein and ferritin. Although not specific to CVD, analysis of these two proteins is valuable in assessing CVD risk.
Oxidative Stress, Glomerular Filtration and Blood Glucose
Because oxidative stress is a component of CVD, the
Comprehensive Cardiovascular Risk Profile blood test measures plasma levels of three
primary antioxidants—coenzyme Q10 and alpha and gamma tocopherol. The test
also looks for elevated serum Homocysteine, which has long been established
as a risk factor, C-Reactive Protein, an inflammatory marker, and finally,
long-term blood glucose homeostasis and glomerular filtration assessments
round out the battery of risk factors analyzed.
see sample report